|
KMID : 0383820160790040289
|
|
Tuberculosis and Respiratory Diseases
2016 Volume.79 No. 4 p.289 ~ p.294
|
|
|
The Prognostic Value of the Charlson's Comorbidity Index in Patients with Prolonged Acute Mechanical Ventilation: A Single Center Experience
|
|
Song Seung-Eon
Lee Sang-Hee
Jo Eun-Jung
Eom Jung-Seop
Mok Jeong-Ha
Kim Mi-Hyun
Kim Ki-Uk
Lee Min-Ki
Lee Kwang-Ha
|
|
|
Abstract
|
|
|
Background : The aim of our study was to evaluate the prognostic value of Charlson's weighted index of comorbidities (WIC) in patients with prolonged acute mechanical ventilation (PAMV, ventilator care ≥96 hours).
Methods : We retrospectively enrolled 299 Korean PAMV patients who were admitted in a medical intensive care unit (ICU) of a university-affiliated tertiary care hospital between 2008 and 2013. Survivors were defined as patients who survived for 60 days after ICU admission.
Results : The patients' mean age was 65.1±14.1 years and 70.6% were male. The mean ICU and hospital length of stay was 21.9±19.7 and 39.4±39.1 days, respectively. In addition, the 60-day mortality rate after ICU admission was 35.5%. The mean WIC was 2.3±1.8, with significant differences between nonsurvivors and survivors (2.7±2.1 vs. 2.1±1.7, p<0.05). The area under the curve of receiver-operating-characteristics curve for WIC was 0.593 (95% confidence interval [CI], 0.523?0.661; p<0.05). Based on Kaplan-Meier curves of 60-day survival, WIC ≥5 had statistically lower survival than WIC <5 (log-rank test, p<0.05). In a multivariate Cox proportional hazard model, WIC ≥5 was associated with poor prognosis (hazard ratio, 1.901; 95% CI, 1.140?3.171; p<0.05). The mortality rate of patients with WIC ≥5 was 54.2%.
Conclusion : Our study showed a WIC score ≥5 might be helpful in predicting 60-day mortality in PAMV patients.
|
|
|
KEYWORD
|
|
|
Intensive Care Units, Comorbidity, Respiration, Artificial, Prognosis
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|
|